Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081899 | 0.83 | GLA (0.38) | GLASTING1SLC11A2MTNR1AMTNR1B | |
| SCHEMBL19445519 | 0.79 | SLC11A2 (0.49) | GLASTING1SLC11A2MTNR1AMTNR1B | |
| SCHEMBL15892075 | 0.77 | MCL1 (0.42) | GLASTING1SLC11A2MTNR1AMTNR1B | |
| SCHEMBL4690679 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2GLASTING1SLC11A2 | |
| SCHEMBL15890445 | 0.75 | SLC11A2 (0.46) | GLASTING1SLC11A2MTNR1AMTNR1B | |
| SCHEMBL4690070 | 0.75 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL11551571 | 0.71 | PDCD1 (0.35) | SLC11A2MTNR1AMTNR1BALDH1A1PDCD1 | |
| SCHEMBL7829502 | 0.70 | ALDH1A1 (0.39) | GABRA1GABRB2ALDH1A1TSHRKDM4E | |
| SCHEMBL7824589 | 0.70 | PDCD1 (0.43) | GLASTING1SLC11A2PDCD1CD274 | |
| SCHEMBL6219249 | 0.70 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |