Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.72 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693822 | 0.91 | PTGER4 (0.60) | PTGER4HDAC1HDAC2HDAC4 | |
| SCHEMBL4693627 | 0.91 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL4687696 | 0.89 | PTGER4 (0.57) | PTGER4HDAC1HDAC2ADAMTS4MMP13 | |
| SCHEMBL3538400 | 0.84 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL4688546 | 0.82 | PTGER4 (0.50) | PTGER4PPARD | |
| SCHEMBL4691618 | 0.82 | PTGER4 (0.55) | PTGER4PPARD | |
| SCHEMBL4693788 | 0.81 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL4691616 | 0.79 | PTGER4 (0.72) | PTGER4 | |
| SCHEMBL4693615 | 0.77 | PTGER4 (0.53) | PTGER4FFAR4FFAR1PPARA | |
| SCHEMBL4687872 | 0.76 | PTGER4 (0.73) | PTGER4FFAR4FFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |