Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690516 | 0.91 | PTGER4 (0.72) | PTGER4HDAC1HDAC2HDAC4 | |
| SCHEMBL3537655 | 0.85 | PTGER4 (0.82) | PTGER4HDAC1HDAC2MRGPRX4CFD | |
| SCHEMBL4693627 | 0.81 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL4691524 | 0.80 | PTGER4 (0.56) | PTGER4MRGPRX4NR4A2MCL1 | |
| SCHEMBL4688546 | 0.80 | PTGER4 (0.50) | PTGER4 | |
| SCHEMBL4691618 | 0.80 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL4687696 | 0.80 | PTGER4 (0.57) | PTGER4HDAC1HDAC2 | |
| SCHEMBL3538400 | 0.75 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL4693680 | 0.73 | PTGER4 (0.74) | PTGER4 | |
| SCHEMBL4693788 | 0.72 | PTGER4 (0.70) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |