Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691618 | 0.94 | PTGER4 (0.55) | PTGER4LMNAPPARDMAPTALDH1A1 | |
| SCHEMBL3534956 | 0.86 | PTGER4 (0.69) | PTGER4LMNAARPPARDMAPT | |
| SCHEMBL4691006 | 0.84 | PTGER4 (0.64) | PTGER4LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL4690516 | 0.82 | PTGER4 (0.72) | PTGER4PPARD | |
| SCHEMBL4690777 | 0.82 | PTGER4 (0.51) | PTGER4LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL4693822 | 0.80 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL3533979 | 0.80 | PTGER4 (0.71) | PTGER4LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL4690870 | 0.77 | MAOB (0.52) | PTGER4LMNAMAOBAKR1C3AKR1C2 | |
| SCHEMBL4693627 | 0.76 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL4691034 | 0.75 | PTGER4 (0.51) | PTGER4LMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |