Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.57 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690516 | 0.89 | PTGER4 (0.72) | PTGER4MMP13HDAC1HDAC2ADAMTS4 | |
| SCHEMBL4693627 | 0.86 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL3534872 | 0.85 | PTGER4 (0.79) | PTGER4MMP2MMP3MMP13MMP1 | |
| SCHEMBL4686978 | 0.83 | PTGER4 (0.73) | PTGER4MMP2 | |
| SCHEMBL4693822 | 0.80 | PTGER4 (0.60) | PTGER4HDAC1HDAC2 | |
| SCHEMBL4687633 | 0.74 | PTGER4 (0.56) | PTGER4MMP2MMP3MMP13MMP1 | |
| SCHEMBL4691618 | 0.74 | PTGER4 (0.55) | PTGER4HPGDPPARD | |
| SCHEMBL4688546 | 0.74 | PTGER4 (0.50) | PTGER4PPARD | |
| SCHEMBL3538400 | 0.73 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL4687872 | 0.73 | PTGER4 (0.73) | PTGER4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |