SCHEMBL4690548

SCHEMBL4690548

Brc1ccc2c3cccc4cccc(c5cccc1c52)c43.NC(=O)NC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.42
GAA P10253 4/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 6/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
MTNR1A P48039 1/20 0.36
TYMS P04818 1/20 0.35
RXFP1 Q9HBX9 2/20 0.35
HPGD P15428 3/20 0.34
CYP1A2 P05177 2/20 0.34
THRB P10828 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 3/20 0.34
MMP3 P08254 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
EPHX1 P07099 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128656 0.86 GAA (0.52) GAAKDM4EALDH1A1MEN1KMT2A
SCHEMBL2332052 0.86 GAA (0.52) GAAKDM4EALDH1A1MEN1KMT2A
Carbamic Acid SCHEMBL3399474 0.83 GAA (0.48) GAAKDM4EALDH1A1MEN1KMT2A
SCHEMBL1187914 0.82 ALDH1A1 (0.48) SLC9A1ALDH1A1TYMSRXFP1HPGD
SCHEMBL9153213 0.79 GAA (0.37) SLC9A1GAAKDM4EALDH1A1MEN1
SCHEMBL6255235 0.79 SLC9A1 (0.37) SLC9A1GAAKDM4EALDH1A1MEN1
SCHEMBL6239368 0.77 GAA (0.39) SLC9A1GAAKDM4EALDH1A1MEN1
SCHEMBL2218415 0.76 ALDH1A1 (0.41) GAAKDM4EALDH1A1MEN1KMT2A
SCHEMBL11204484 0.75 GAA (0.42) GAAKDM4EALDH1A1MEN1KMT2A
Pyrene SCHEMBL27932533 0.74 ALDH1A1 (0.52) GAAKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874773-A1 HEXARYLENE AND PENTARYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2008-01-09 EP disclosed
WO-2006111511-A1 HEXARYLENE AND PENTARYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2006-10-26 WO disclosed