Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567559 | 0.91 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL1566620 | 0.90 | MTNR1A (0.66) | MTNR1AMTNR1B | |
| SCHEMBL1566624 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4691174 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL29742182 | 0.76 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL4685349 | 0.74 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL1566672 | 0.73 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL1387225 | 0.69 | MTNR1A (0.87) | MTNR1AMTNR1B | |
| SCHEMBL123755 | 0.67 | MTNR1B (1.00) | MTNR1AMTNR1B | |
| SCHEMBL124798 | 0.67 | MTNR1B (0.67) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100443480-C | Tricyclic compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-100441574-C | Tricyclic compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-12-10 | — | — | CN | disclosed |
| EP-0885210-B2 | Tricylic compounds having binding affinity for melatonin receptors, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2008-06-18 | — | — | EP | disclosed |
| CN-1900067-A | Tricyclic compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2007-01-24 | — | — | CN | disclosed |
| CN-1727339-A | Tricyclic compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-01 | — | — | CN | disclosed |
| EP-1550655-A1 | Bicyclic intermediates | Takeda Pharmaceutical Company Limited (JP) | 2005-07-06 | — | — | EP | disclosed |
| EP-0885210-B1 | Tricylic compounds having binding affinity for melatonin receptors, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-1199304-A1 | Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders | Takeda Chemical Industries, Ltd. (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-6218429-B1 | TREATING MELATONIN RELATED DISORDERS (E.G. CIRCARDIAN RHYTHMS, SLEEP-AWAKE CYCLES, TIME ZONE CHANGES, SLEEP DISORDERS) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-6034239-A | BINDIG TO MELATONIN RECEPTORS; SLEEP DISORDERS; GLANDULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| CN-1212691-A | Tricyclic compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-03-31 | — | — | CN | disclosed |