Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28007503 | 0.88 | POLB (0.60) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL24073601 | 0.87 | HDAC3 (0.58) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL30786693 | 0.81 | CES2 (0.61) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL1994068 | 0.81 | CES2 (0.61) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL1423257 | 0.81 | ALDH1A1 (0.55) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL4766873 | 0.79 | KCNK3 (0.72) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL1972781 | 0.79 | ALDH1A1 (0.63) | HDAC3HDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL20557435 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1POLBGAAHTTMEN1 | |
| SCHEMBL3673984 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1POLBNPSR1GAAMEN1 | |
| SCHEMBL8740128 | 0.78 | KMT2A (0.70) | ALDH1A1POLBNPSR1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054875-B1 | INSECTICIDAL DIHYDRO-OXADIAZINES, -THIADIAZINES AND -TRIAZINES | CHEMTURA CORP (US) | 2008-04-23 | — | — | EP | disclosed |
| CN-1162410-C | Insecticidal dihydrooxadiazines, dihydrothiadiazines and dihydrotriazines | �Ϻ���ͨ��ѧ | 2004-08-18 | — | — | CN | disclosed |
| CN-1290257-A | Insecticidal dihydro-oxadiazines, -thiadiazines and triazines | UNIROYAL CHEM CO INC (US) | 2001-04-04 | — | — | CN | disclosed |
| US-6197766-B1 | CONTROLLING PLANT INSECTS | UNIROYAL CHEMICAL COMPANY, INC. AND UNIROYAL CHEMICAL CO. | 2001-03-06 | — | — | US | disclosed |
| EP-1054875-A1 | INSECTICIDAL DIHYDRO-OXADIAZINES, -THIADIAZINES AND -TRIAZINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6011034-A | Insecticidal dihydrooxadiazine compounds | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-01-04 | — | — | US | disclosed |
| WO-1999041245-A1 | INSECTICIDAL DIHYDRO-OXADIAZINES, -THIADIAZINES AND -TRIAZINES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-08-19 | — | — | WO | disclosed |