Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691034 | 0.89 | PTGER4 (0.51) | PTGER4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL4690777 | 0.87 | PTGER4 (0.51) | PTGER4MAPTKDM4EALDH1A1SLC26A4 | |
| SCHEMBL3535902 | 0.85 | PTGER4 (0.87) | PTGER4MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4688546 | 0.84 | PTGER4 (0.50) | PTGER4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL4693788 | 0.81 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL4690870 | 0.80 | MAOB (0.52) | PTGER4TDP1LMNAACHEMAOB | |
| SCHEMBL3535669 | 0.78 | PTGER4 (1.00) | PTGER4MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4691618 | 0.77 | PTGER4 (0.55) | PTGER4MAPTALDH1A1POLBHPGD | |
| SCHEMBL4694643 | 0.75 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL4692290 | 0.75 | PTGER4 (0.71) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |