Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688386 | 0.93 | LMNA (0.57) | MAOBLMNAPTGER4MAOACASP3 | |
| SCHEMBL3534753 | 0.87 | PTGER4 (0.63) | MAOBLMNAPTGER4AKR1C3AKR1C2 | |
| SCHEMBL3538811 | 0.80 | PTGER4 (0.65) | MAOBLMNAPTGER4MAOACASP3 | |
| SCHEMBL4691006 | 0.80 | PTGER4 (0.64) | MAOBLMNAPTGER4AKR1C3AKR1C2 | |
| SCHEMBL4686959 | 0.79 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL4690777 | 0.78 | PTGER4 (0.51) | MAOBLMNAPTGER4AKR1C3AKR1C2 | |
| SCHEMBL4688546 | 0.77 | PTGER4 (0.50) | MAOBLMNAPTGER4AKR1C3AKR1C2 | |
| SCHEMBL4691034 | 0.73 | PTGER4 (0.51) | LMNAPTGER4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4691702 | 0.72 | PTGER4 (0.59) | PTGER4NPC1RAB9ATDP1 | |
| SCHEMBL11716004 | 0.71 | MAOB (0.59) | MAOBACHEMAOANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |