Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CCL5 | P13501 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694458 | 0.89 | CCR5 (0.53) | CCR5CCL5 | |
| SCHEMBL4693284 | 0.87 | CCR5 (0.53) | CCR5CCL5 | |
| SCHEMBL4691304 | 0.85 | CCR5 (0.53) | CCR5CCL5 | |
| SCHEMBL4696366 | 0.84 | CCR5 (0.46) | CCR5CCL5GRIN2B | |
| SCHEMBL4694118 | 0.84 | KCNK3 (0.51) | CCR5ALDH1A1SMN1; SMN2 | |
| SCHEMBL4694493 | 0.83 | CCR5 (0.53) | CCR5CCL5KCNH2 | |
| SCHEMBL4693578 | 0.83 | CCR5 (0.53) | CCR5TSHRCCL5ALDH1A1 | |
| SCHEMBL4693040 | 0.83 | CCR5 (0.51) | CCR5TSHR | |
| SCHEMBL4693123 | 0.82 | CCR5 (0.50) | CCR5CCL5ALDH1A1 | |
| SCHEMBL4691195 | 0.82 | HCRTR1 (0.52) | CCR5CCL5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |