Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694021 | 0.81 | RAB9A (0.43) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4693177 | 0.81 | GRN (0.48) | CNR1CNR2MEN1KMT2ASLC6A2 | |
| SCHEMBL5262774 | 0.80 | SLC6A9 (0.54) | MEN1KMT2AGAASLC6A2SLC6A4 | |
| SCHEMBL4688836 | 0.80 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL4691613 | 0.79 | CNR1 (0.62) | CNR1CNR2ALDH1A1MAPTHTT | |
| SCHEMBL2652057 | 0.79 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL2653467 | 0.79 | CNR1 (0.62) | CNR1CNR2ALDH1A1MAPTHTT | |
| SCHEMBL4688708 | 0.78 | CNR1 (0.41) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL13114017 | 0.78 | MTNR1A (0.49) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4690861 | 0.77 | CNR1 (0.63) | CNR1CNR2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |