Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903869 | 0.83 | ALDH1A1 (0.65) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL12808726 | 0.83 | FOLH1 (0.56) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| Benzoic Acid SCHEMBL11315587 | 0.81 | TSHR (0.58) | TP53PKMALDH1A1KMT2A | |
| SCHEMBL111422 | 0.81 | ALDH1A1 (0.64) | TP53SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL4351183 | 0.81 | ALDH1A1 (0.64) | TP53SMN1; SMN2RAB9AALDH1A1NPC1 | |
| Benzene SCHEMBL19304565 | 0.81 | ALDH1A1 (0.64) | TP53SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL25284732 | 0.81 | MRGPRX4 (0.56) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL371526 | 0.80 | FOLH1 (0.70) | FOLH1MRGPRX4KMT2ANR4A2 | |
| SCHEMBL1560391 | 0.80 | CYP4F2 (0.53) | ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL1992145 | 0.80 | CYP4F2 (0.53) | ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |