Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695548 | 0.86 | CCR1 (0.42) | CCR1BRD4ALDH1A1ALK | |
| SCHEMBL4310454 | 0.81 | CCR1 (0.43) | CCR1BRD4ALDH1A1 | |
| SCHEMBL4016748 | 0.81 | CCR1 (0.56) | CCR1ALDH1A1CYP2C19KCNH2 | |
| SCHEMBL3633791 | 0.80 | CCR1 (0.42) | CCR1BRD4 | |
| SCHEMBL3636885 | 0.79 | CCR1 (0.41) | CCR1BRD4 | |
| SCHEMBL3639637 | 0.79 | CCR1 (0.40) | CCR1BRD4ALDH1A1 | |
| SCHEMBL3632086 | 0.78 | CCR1 (0.42) | CCR1BRD4ALK | |
| SCHEMBL3636662 | 0.77 | CCR1 (0.43) | CCR1BRD4CYP2C19KCNH2ALK | |
| SCHEMBL3639158 | 0.77 | RAB9A (0.42) | CCR1 | |
| SCHEMBL5289677 | 0.77 | CCR1 (0.42) | CCR1BRD4ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906965-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |