Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693246 | 0.86 | CCR1 (0.43) | CCR1ALKALDH1A1BRD4 | |
| SCHEMBL4310454 | 0.86 | CCR1 (0.43) | CCR1ALDH1A1MAPTLMNABRD4 | |
| SCHEMBL3639637 | 0.83 | CCR1 (0.40) | CCR1ALDH1A1MAPTLMNABRD4 | |
| SCHEMBL3633791 | 0.82 | CCR1 (0.42) | CCR1MAPTLMNABRD4 | |
| SCHEMBL3636885 | 0.82 | CCR1 (0.41) | CCR1MAPTLMNABRD4 | |
| SCHEMBL3636906 | 0.81 | CCR1 (0.42) | CCR1ALKALDH1A1RXRAGRIN1 | |
| SCHEMBL4016748 | 0.81 | CCR1 (0.56) | CCR1ALDH1A1MAPTLMNA | |
| SCHEMBL3635666 | 0.80 | CCR1 (0.50) | CCR1ALKMAPT | |
| SCHEMBL3636662 | 0.80 | CCR1 (0.43) | CCR1ALKMAPTLMNABRD4 | |
| SCHEMBL3634696 | 0.80 | CCR1 (0.46) | CCR1ALKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906965-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |