Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.55 |
| ▸ | NOS1 | P29475 | 4/20 | 0.55 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12990509 | 0.82 | L3MBTL1 (0.46) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL28889354 | 0.81 | CA12 (0.52) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL28219587 | 0.79 | MAPT (0.58) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL20113451 | 0.79 | L3MBTL1 (0.53) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL4829383 | 0.79 | IDO1 (0.58) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL1397310 | 0.78 | IDO1 (0.65) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL6963636 | 0.78 | TDP1 (0.59) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL11291081 | 0.78 | CYP2C19 (0.70) | IDO1NOS1NOS3NOS2TDP1 | |
| Ethylene SCHEMBL28219597 | 0.76 | MAPT (0.55) | IDO1NOS1NOS3NOS2TDP1 | |
| SCHEMBL3048336 | 0.76 | TDP1 (0.79) | IDO1NOS1NOS3NOS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065123-A1 | Synthetic Antibodies | NATIONAL INSTITUTES OF HEALTH | 2012-03-15 | — | — | US | disclosed |