Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 6/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589963 | 0.87 | MEN1 (0.58) | L3MBTL1TDP1MEN1KMT2AHDAC3 | |
| SCHEMBL45253 | 0.84 | TDP1 (0.61) | L3MBTL1TDP1CYP2C19IDO1NOS3 | |
| SCHEMBL14158550 | 0.82 | L3MBTL1 (0.57) | L3MBTL1TDP1CYP2C19CYP3A4MEN1 | |
| SCHEMBL28219587 | 0.81 | MAPT (0.58) | L3MBTL1TDP1CYP2C19IDO1NOS3 | |
| SCHEMBL8922205 | 0.80 | EPHX2 (0.61) | TDP1CYP2C19CYP3A4KMT2AEPHX2 | |
| SCHEMBL6963636 | 0.79 | TDP1 (0.59) | L3MBTL1TDP1CYP2C19IDO1NOS3 | |
| SCHEMBL469338 | 0.79 | IDO1 (0.55) | L3MBTL1TDP1CYP2C19IDO1NOS3 | |
| SCHEMBL28889354 | 0.79 | CA12 (0.52) | L3MBTL1TDP1CYP2C19IDO1NOS3 | |
| SCHEMBL11291081 | 0.79 | CYP2C19 (0.70) | L3MBTL1TDP1CYP2C19CYP3A4IDO1 | |
| Ethylene SCHEMBL28219597 | 0.78 | MAPT (0.55) | L3MBTL1TDP1CYP2C19IDO1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159448-A1 | MOLECULAR RENAL PROBES FOR DETECTING ACUTE KIDNEY INJURY | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-08-06 | — | — | WO | disclosed |
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | L3MBTL1 3799/4885TDP1 2513/4885CYP2C19 2738/4885 |
| US-10633403-B2 | N-heterocyclic phosphines | NANP, PPIP5K2, PHPT1 | L3MBTL1 3799/4885TDP1 2513/4885CYP2C19 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.