Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14257265 | 0.90 | KDM4D (0.43) | KDM4DTGFBR1KDM4EPDE2AALDH1A1 | |
| SCHEMBL4691354 | 0.81 | KDM4D (0.44) | KDM4DTGFBR1KDM4EPDE2AALDH1A1 | |
| SCHEMBL4692101 | 0.76 | PDE2A (0.41) | KDM4DTGFBR1KDM4EPDE2AALDH1A1 | |
| SCHEMBL5466991 | 0.75 | KDM4E (0.37) | KDM4EPDE2AALDH1A1HPGDTRPV1 | |
| SCHEMBL14587905 | 0.74 | TGFBR1 (0.40) | KDM4DTGFBR1KDM4EPDE2AALDH1A1 | |
| SCHEMBL5324293 | 0.70 | KDM4E (0.43) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL18863632 | 0.70 | CSNK2A1 (0.44) | KDM4DKDM4EALDH1A1HPGDCLK4 | |
| SCHEMBL5444175 | 0.68 | TRPV1 (0.35) | TRPV1 | |
| SCHEMBL4691853 | 0.67 | CSNK2A1 (0.44) | KDM4DKDM4EALDH1A1HPGDCDK2 | |
| SCHEMBL11464623 | 0.66 | KDM4E (0.62) | KDM4DTGFBR1KDM4EPDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037828-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037828-A1 | Pyrazolopyrimidines | DPYD, RPLP2, Q6ZSR9 | KDM4D 2309/4885TGFBR1 4264/4885KDM4E 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.