Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323810 | 0.81 | KDM4E (0.44) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL14414314 | 0.81 | KDM4E (0.47) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL2796946 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL4691853 | 0.75 | CSNK2A1 (0.44) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL5351754 | 0.72 | CDK2 (0.41) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL5351750 | 0.72 | CDK2 (0.41) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL5345618 | 0.71 | CDK2 (0.39) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL5345610 | 0.71 | CDK2 (0.39) | KDM4ECDK2ALDH1A1LMNAPOLB | |
| SCHEMBL18863632 | 0.70 | CSNK2A1 (0.44) | KDM4ECDK2ALDH1A1KDM4DCSNK2A1 | |
| SCHEMBL4693576 | 0.70 | KDM4D (0.45) | KDM4ECDK2ALDH1A1KDM4DCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101859-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER | BASF SE (DE) | 2007-09-13 | — | — | WO | disclosed |