Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14257394 | 0.89 | CSNK2A1 (0.42) | CSNK2A1KDM4ECDK2ALDH1A1HPGD | |
| SCHEMBL4691830 | 0.81 | CSNK2A1 (0.46) | CSNK2A1KDM4ECDK2ALDH1A1HPGD | |
| SCHEMBL4503405 | 0.77 | NOTUM (0.36) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL4491443 | 0.76 | GPR39 (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL5324293 | 0.75 | KDM4E (0.43) | CSNK2A1KDM4ECDK2ALDH1A1HPGD | |
| SCHEMBL4510395 | 0.75 | HSD11B1 (0.34) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL14463731 | 0.74 | CDK2 (0.42) | CSNK2A1KDM4ECDK2ALDH1A1HPGD | |
| SCHEMBL5239519 | 0.73 | PDE10A (0.38) | KDM4ECDK2CNR2 | |
| SCHEMBL14374440 | 0.73 | HTT (0.45) | CSNK2A1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL18863632 | 0.73 | CSNK2A1 (0.44) | CSNK2A1KDM4ECDK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694681-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| EP-1697372-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| EP-1697372-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1513843-B1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2007-07-04 | — | — | EP | disclosed |
| US-20060276478-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1694680-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| EP-1694679-A1 | PYRAZOLOPYRIMIDINES AS FUNGICIDAL ACTIVE INGREDIENTS | Bayer CropScience Aktiengesellschaft (DE) | 2006-08-30 | — | — | EP | disclosed |
| EP-1694681-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | disclosed |
| WO-2005056558-A1 | PYRAZOLOPYRIMIDINES AS FUNGICIDAL ACTIVE INGREDIENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056556-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056559-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | CSNK2A1 2382/4885KDM4E 3455/4885CDK2 154/4885 |
| US-20070197540-A1 | Pyrazolopyrimidines | QDPR, Q6ZSR9, RPLP2 | CSNK2A1 2716/4885KDM4E 2820/4885CDK2 117/4885 |
| US-20070244111-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | CSNK2A1 3066/4885KDM4E 3362/4885CDK2 200/4885 |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | PNPO, CYP4X1, CYP1B1 | CSNK2A1 4793/4885KDM4E 1894/4885CDK2 1161/4885 |
| US-20060276478-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | CSNK2A1 3066/4885KDM4E 3362/4885CDK2 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.