Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138894 | 0.82 | POLB (0.49) | POLBMAPTPDK2 | |
| SCHEMBL5258807 | 0.76 | PLK1 (0.50) | HIF1AELANE | |
| SCHEMBL4693156 | 0.73 | MEN1 (0.38) | KEAP1NFE2L2MAPK1RIPK2UGCG | |
| SCHEMBL2512530 | 0.73 | CA1 (0.67) | HIF1AMAPK1CA1CA2CA4 | |
| SCHEMBL3133796 | 0.73 | CA1 (0.63) | HIF1AMAPK1CA1CA2CA4 | |
| SCHEMBL4692428 | 0.72 | KEAP1 (0.44) | KEAP1NFE2L2MAPK1RIPK2L3MBTL1 | |
| SCHEMBL20558012 | 0.71 | ELANE (0.36) | ELANE | |
| SCHEMBL6163498 | 0.70 | CA4 (0.69) | HIF1ACA1CA2CA4CA9 | |
| SCHEMBL4697047 | 0.69 | ELANE (0.34) | L3MBTL1POLBSMN1; SMN2ELANE | |
| SCHEMBL29375980 | 0.68 | KMT2A (0.46) | L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |