SCHEMBL4693784

SCHEMBL4693784

FCc1ccc2[nH][c]cc2c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4693144 0.86 MEN1 (0.31) MEN1KMT2A
SCHEMBL17844466 0.79 CYP1A2 (0.47) MEN1KMT2A
SCHEMBL4694683 0.79 MEN1 (0.31) MEN1KMT2A
SCHEMBL8665561 0.79 CA2 (0.38) MEN1KMT2A
SCHEMBL9740027 0.75 CALM1 (0.44) MEN1KMT2A
SCHEMBL17844546 0.75 XDH (0.44) MEN1KMT2A
SCHEMBL7526047 0.71 CYP1A2 (0.44) KMT2A
SCHEMBL207531 0.71 AHR (0.50)
SCHEMBL27825995 0.71 AHR (0.55)
SCHEMBL207737 0.67 CYP2A6 (0.50) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879896-A1 IMIDAZOPYRIDAZINE COMPOUNDS ELI LILLY AND COMPANY (US) 2008-01-23 EP disclosed
WO-2006107784-A1 IMIDAZOPYRIDAZINE COMPOUNDS ELI LILLY AND COMPANY (US) 2006-10-12 WO disclosed