Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3629625 | 0.98 | GRIN2B (0.45) | GRIN2BGRIN1GBA1NOS2GRIN2D | |
| Hydrochloric Acid SCHEMBL19385070 | 0.89 | GRIN2B (0.42) | GRIN2BGRIN1GBA1NOS2GRIN2D | |
| SCHEMBL19385203 | 0.72 | NOS2 (0.47) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL873951 | 0.71 | NOS2 (0.46) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL3536653 | 0.70 | GBA1 (0.53) | GBA1SIGMAR1 | |
| SCHEMBL19986856 | 0.70 | GRIN2B (0.47) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL45769 | 0.68 | GRIN2B (0.68) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL8657131 | 0.68 | GBA1 (0.50) | GBA1SIGMAR1 | |
| SCHEMBL1477277 | 0.68 | GBA1 (0.50) | GBA1 | |
| Hydrochloric Acid SCHEMBL9310454 | 0.67 | GBA1 (0.49) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954696-A2 | 2-PHENOXY-N-(1,3,4-THIADIZOL-2-YL)PYRIDIN-3-AMINE DERIVATIVES AND RELATED COMPOUNDS AS P2Y1 RECEPTOR INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | Bristol-Myers Squibb Company (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2006078621-A9 | 2-PHENOXY-N- (1, 3 , 4-THIADIZOL-2-YL) PYRIDIN-3-AMINE DERIVATIVES AND RELATED COMPOUNDS AS P2Y1 RECEPTOR INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2006078621-A2 | 2-PHENOXY-N- (1, 3 , 4-THIADIZOL-2-YL) PYRIDIN-3-AMINE DERIVATIVES AND RELATED COMPOUNDS AS P2Y1 RECEPTOR INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-27 | — | — | WO | disclosed |