SCHEMBL45769

SCHEMBL45769

NC(N)=NCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 10/20 0.68
GRIN1 Q05586 8/20 0.68
GRIN2D O15399 4/20 0.68
GRIN3B O60391 4/20 0.68
GRIN2A Q12879 4/20 0.68
GRIN2C Q14957 4/20 0.68
GRIN3A Q8TCU5 4/20 0.68
NOS2 P35228 1/20 0.65
HTR3A P46098 2/20 0.61
HTR3E A5X5Y0 1/20 0.61
HTR3B O95264 1/20 0.61
HTR3D Q70Z44 1/20 0.61
HTR3C Q8WXA8 1/20 0.61
SIGMAR1 Q99720 2/20 0.59
HTR1A P08908 1/20 0.59
ADRA2A P08913 1/20 0.59
MAOA P21397 1/20 0.59
DRD1 P21728 1/20 0.59
SLC6A2 P23975 1/20 0.59
ADRA1A P35348 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7206541 0.98 GRIN2B (0.65) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
Hydrochloric Acid SCHEMBL4629266 0.98 GRIN2B (0.72) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
Sulfuric Acid SCHEMBL4014387 0.89 LMNA (0.65) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL1737052 0.87 GRIN1 (0.62) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
Amphetamine SCHEMBL28092355 0.83 TAAR1 (0.66) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL10425011 0.82 GRIN2B (0.52) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL1736065 0.82 TAAR1 (0.67) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL1736064 0.82 TAAR1 (0.67) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL5670677 0.82 LTA4H (0.55) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A
SCHEMBL14291059 0.81 NOS2 (0.96) GRIN2BGRIN1GRIN2DGRIN3BGRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101904-A1 NOREPINEPHRINE TRANSPORTER-TARGETED PRODRUGS FOR CANCER THERAPY THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-05-15 WO claimed
CN-119950749-A Polymer-based macromolecular prodrugs 费城儿童医院 2025-05-09 CN claimed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US claimed
CN-113557037-B Radiopharmaceuticals for diagnostic/therapeutic use in nuclear medicine and radioguided medicine 罗马大学 2024-08-09 CN claimed
WO-2024139692-A1 LIGHT-EMITTING APPARATUS AND MANUFACTURING METHOD THEREFOR, AND DISPLAY DEVICE TCL科技集团股份有限公司 2024-07-04 WO claimed
CN-118284106-A Light emitting device, method of manufacturing the same, and display apparatus TCL科技集团股份有限公司 2024-07-02 CN claimed
EP-4351650-A1 COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS NanoPharmaceuticals LLC (US) 2024-04-17 EP claimed
WO-2024068510-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-2 BASF SE (DE) 2024-04-04 WO claimed
WO-2024068508-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 BASF SE (DE) 2024-04-04 WO claimed
WO-2024068509-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 BASF SE (DE) 2024-04-04 WO claimed
EP-0624475-B1 Ink tank, head cartridge and ink jet printing apparatus CANON KK (JP) 1999-03-31 EP claimed
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP claimed
CN-1083473-A New imidazolium compounds and pharmaceutical composition thereof SMITHKLINE BEECHAM CORP (US) 1994-03-09 CN claimed
EP-0283990-B1 A heat-resistant photosensitive resin composition TOKYO OHKA KOGYO CO LTD (JP) 1994-01-26 EP claimed
EP-0319751-B1 UREA-FORMALDEHYDE RESIN, ITS PREPARATION AND USE Schöllhorn, Wolf-Dietrich (DE) 1993-02-10 EP claimed
EP-0165630-B1 METHOD OF PREPARING A CHLORINATED, BROMINATED, RADIOBROMINATED, IODINATED AND/OR RADIOIODINATED, AROMATIC OR HETEROAROMATIC COMPOUND, AS WELL AS A KIT FOR PREPARING A DIAGNOSTIC COMPOSITION ON THE BASIS OF THIS COMPOUND MALLINCKRODT, INC.(a Missouri corporation) (US) 1989-10-18 EP claimed
EP-0283990-A2 A heat-resistant photosensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 1988-09-28 EP claimed
EP-0280295-A2 A heat-resistant photosensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 1988-08-31 EP claimed
EP-0165630-A2 Method of preparing a chlorinated, brominated, radiobrominated, iodinated and/or radioiodinated, aromatic or heteroaromatic compound, as well as a kit for preparing a diagnostic composition on the basis of this compound MALLINCKRODT, INC.(a Missouri corporation) (US) 1985-12-27 EP claimed
US-4341694-A POLYMERS, 2,6,7-TRIOXA-1-PHOSPHOBICYCLO 2.2.2/OCTANE-4-METHANOL-1-OXIDE BORG-WARNER CORPORATION (US) 1982-07-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO GRIN2B 2635/4885GRIN1 3299/4885GRIN2D 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.