Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801467 | 0.87 | LMNA (0.46) | L3MBTL1ALDH1A1GLAHPGDKMT2A | |
| SCHEMBL8655174 | 0.79 | GBA1 (0.47) | GBA1SLC6A2SLC6A4HRH1L3MBTL1 | |
| SCHEMBL1477277 | 0.79 | GBA1 (0.50) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL9310454 | 0.77 | GBA1 (0.49) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| SCHEMBL9385814 | 0.73 | GBA1 (0.45) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| SCHEMBL20677801 | 0.73 | GBA1 (0.45) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| SCHEMBL11127228 | 0.72 | POLB (0.51) | SLC6A2SLC6A4ALDH1A1SLC6A3 | |
| SCHEMBL11563161 | 0.70 | PAM (0.51) | GBA1HRH1L3MBTL1ALDH1A1KMT2A | |
| Phenylacetic Acid SCHEMBL28337405 | 0.70 | AKR1B1 (0.59) | GBA1L3MBTL1ALDH1A1GLAHPGD | |
| Ethylbenzene SCHEMBL27515696 | 0.69 | TP53 (0.52) | GBA1SLC6A2SLC6A4HRH1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | claimed |