Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232778 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL4695582 | 0.81 | CSNK2A1 (0.39) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL14257400 | 0.73 | LMNA (0.40) | KDM4EALDH1A1LMNAKDM4DHPGD | |
| SCHEMBL14463715 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNAKDM4DHPGD | |
| SCHEMBL26621993 | 0.70 | KDM4E (0.60) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL5230928 | 0.69 | KDM4D (0.43) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL4708598 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL29071794 | 0.68 | KDM4E (0.73) | KDM4EALDH1A1LMNAPOLBRXFP1 | |
| SCHEMBL4693069 | 0.67 | PDE2A (0.41) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL14039397 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1LMNAPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513843-B1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2007-07-04 | — | — | EP | disclosed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | KDM4E 3455/4885ALDH1A1 907/4885LMNA 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.