Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | RORC | P51449 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099561 | 0.88 | RAB9A (0.62) | KMT2AMAPTSMN1; SMN2TP53GAA | |
| SCHEMBL20051726 | 0.86 | KMT2A (0.60) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL20051373 | 0.86 | KMT2A (0.63) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL13753352 | 0.85 | CYP3A4 (0.51) | KMT2AMEN1RORCMAPTCYP3A4 | |
| SCHEMBL7597169 | 0.84 | MAPT (0.67) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL13753896 | 0.84 | L3MBTL1 (0.57) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8947103 | 0.83 | KMT2A (0.60) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL4361418 | 0.83 | RORC (0.65) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL20051330 | 0.83 | KMT2A (0.60) | KMT2AMEN1RORCMAPTSMN1; SMN2 | |
| SCHEMBL7563977 | 0.83 | MAPT (0.66) | KMT2AMEN1RORCMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053227-B1 | PPAR-GAMMA MODULATORS | AMGEN INC (US) | 2008-11-05 | — | — | EP | disclosed |
| US-7439242-B2 | PPARγ modulators | AMGEN INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-6620827-B2 | Peroxisome proliferator-activated receptors-gamma to control lipid metabolism ane obesity; antidiabetic, -inflammatory and -arthritic agents; non-insulin dependent diabetes; antilipemic and -cholesterol agents | TULARIK INC. | 2003-09-16 | — | — | US | disclosed |
| US-20030088103-A1 | PPARgamma modulators | TULARIK INC. (US) | 2003-05-08 | — | — | US | disclosed |
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-20010027200-A1 | PPARgamma modulators | TULARIK INC. | 2001-10-04 | — | — | US | disclosed |
| US-6252078-B1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6248894-B1 | SUBSTITUTED PYRROLES | MONSANTO COMPANY | 2001-06-19 | — | — | US | disclosed |
| US-5998466-A | PREPLANTING | MONSANTO COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1999038845-A1 | PPAR-GAMMA MODULATORS | TULARIK INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030088103-A1 | PPARgamma modulators | PPARG, PPARA, PPARD | KMT2A 3971/4885MEN1 4878/4885RORC 127/4885 |
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | CNPY3, NAT1, CBR3 | KMT2A 3561/4885MEN1 1979/4885RORC 3609/4885 |
| US-20010027200-A1 | PPARgamma modulators | PPARG, PPARA, PPARD | KMT2A 3971/4885MEN1 4878/4885RORC 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.