Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694923 | 0.90 | CCR5 (0.56) | CCR5SLC6A9 | |
| SCHEMBL4692299 | 0.87 | CCR5 (0.58) | CCR5SLC6A9 | |
| SCHEMBL4696921 | 0.79 | CCR5 (0.47) | CCR5SLC6A9 | |
| SCHEMBL4694831 | 0.77 | CCR5 (0.41) | CCR5 | |
| SCHEMBL4696469 | 0.77 | CCR5 (0.41) | CCR5 | |
| SCHEMBL4693075 | 0.75 | CCR5 (0.80) | CCR5 | |
| SCHEMBL4693072 | 0.75 | CCR5 (0.80) | CCR5 | |
| SCHEMBL4696815 | 0.74 | CCR5 (0.40) | CCR5 | |
| SCHEMBL4695429 | 0.74 | CCR5 (0.46) | CCR5SLC6A9 | |
| SCHEMBL4695320 | 0.73 | CCR5 (0.41) | CCR5SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |