Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | HPGD | P15428 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16800347 | 0.88 | RAB9A (0.79) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL11231059 | 0.83 | KDM4E (0.74) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL29435302 | 0.83 | KDM4E (0.74) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL12986344 | 0.83 | KDM4E (0.74) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL8513693 | 0.83 | CA12 (0.81) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL18741340 | 0.82 | KDM4E (1.00) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL5675501 | 0.82 | KDM4E (0.77) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL3081887 | 0.82 | RAB9A (0.70) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL790969 | 0.82 | KDM4E (0.73) | RAB9ATDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL29435304 | 0.82 | KDM4E (0.81) | RAB9ATDP1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | disclosed |
| CN-106470977-B | Water-soluble activatable molecular probe, synthetic intermediate thereof and related detection method | 里昂高等师范学院 | 2021-07-09 | — | — | CN | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| CN-106470977-A | Water solublity can anakmetomeres probe, its synthetic intermediate and related detecting method | 里昂高等师范学院 | 2017-03-01 | — | — | CN | disclosed |
| US-8754179-B2 | Light activated shape memory co-polymers | CORNERSTONE RESEARCH GROUP, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20080021166-A1 | Light Activated Shape Memory Co-Polymers | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2008-01-24 | — | — | US | disclosed |
| EP-1799771-A2 | LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007001407-A2 | LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | RAB9A 4525/4885TDP1 2102/4885ALDH1A1 426/4885 |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | SI, GUSB, ABCG2 | RAB9A 4525/4885TDP1 2102/4885ALDH1A1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.