Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 4/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924545 | 1.00 | LMNA (0.40) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL4699450 | 0.92 | ANPEP (0.33) | LMNAALDH1A1ANPEPENPEP | |
| SCHEMBL914994 | 0.92 | ANPEP (0.33) | LMNAALDH1A1ANPEPENPEP | |
| SCHEMBL915730 | 0.89 | LMNA (0.41) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL4699739 | 0.89 | LMNA (0.41) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL915925 | 0.88 | ANPEP (0.35) | LMNAANPEPENPEP | |
| SCHEMBL4697132 | 0.88 | ANPEP (0.35) | LMNAANPEPENPEP | |
| SCHEMBL915959 | 0.83 | MMP1 (0.40) | LMNAANPEPENPEP | |
| SCHEMBL914976 | 0.83 | ANPEP (0.33) | LMNAANPEPENPEP | |
| SCHEMBL4699309 | 0.83 | ANPEP (0.33) | LMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |