Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HGFAC | Q04756 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751170 | 0.87 | ALOX5 (0.57) | HGFACALOX5LMNAKDM4EALOX12 | |
| SCHEMBL1016235 | 0.85 | HGFAC (0.58) | HGFACALOX5LMNAKDM4EALOX12 | |
| SCHEMBL28193618 | 0.83 | HSD17B10 (0.59) | HGFACLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL27730499 | 0.83 | MDM2 (0.54) | HGFACALOX5LMNAKDM4EALOX12 | |
| Ammonia Solution, Strong SCHEMBL27995845 | 0.82 | CES2 (0.58) | HGFACALOX5LMNAKDM4EL3MBTL1 | |
| SCHEMBL28193616 | 0.82 | HSD17B10 (0.61) | HGFACLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL7186306 | 0.80 | HSD17B10 (0.59) | HGFACLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL29617475 | 0.80 | MAPT (0.63) | HGFACLMNATDP1ALDH1A1KMT2A | |
| SCHEMBL3793561 | 0.80 | MAPT (0.63) | HGFACLMNATDP1ALDH1A1KMT2A | |
| SCHEMBL27373763 | 0.80 | SLC6A3 (0.61) | ALOX5LMNAHSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987037-A2 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007097470-A2 | FUSED NITROGEN- COMPRISING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-30 | — | — | WO | disclosed |