Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697179 | 1.00 | MEN1 (0.53) | MEN1KMT2AMAPTALOX12NPC1 | |
| SCHEMBL4698447 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL4698577 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17561003 | 0.80 | MAPT (0.56) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL4701251 | 0.77 | RAB9A (0.55) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL4698606 | 0.76 | MAPT (0.50) | MEN1KMT2AMAPTNPC1NPSR1 | |
| SCHEMBL4698601 | 0.76 | MAPT (0.50) | MEN1KMT2AMAPTNPC1NPSR1 | |
| SCHEMBL4698438 | 0.74 | LMNA (0.51) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL4697181 | 0.74 | RXFP3 (0.52) | MAPTALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL4701009 | 0.73 | KMT2A (0.74) | MEN1KMT2AMAPTALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |