Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704345 | 0.90 | PARP1 (0.58) | PARP1 | |
| SCHEMBL4698407 | 0.85 | PARP1 (0.72) | PARP1 | |
| SCHEMBL4700129 | 0.84 | LMNA (0.51) | PARP1 | |
| SCHEMBL4698690 | 0.82 | PARP1 (0.55) | PARP1 | |
| SCHEMBL4702676 | 0.81 | PARP1 (0.48) | PARP1 | |
| SCHEMBL4697638 | 0.81 | PARP1 (0.48) | PARP1 | |
| SCHEMBL4700307 | 0.81 | PARP1 (0.55) | PARP1 | |
| SCHEMBL4700486 | 0.80 | PARP1 (0.49) | PARP1 | |
| SCHEMBL4699193 | 0.79 | PARP1 (0.59) | PARP1 | |
| SCHEMBL4700866 | 0.79 | PARP1 (0.52) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427708-B1 | AMINO-PHTHALAZINONE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER ITALIA SRL (IT) | 2008-09-10 | — | — | EP | claimed |