Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28418917 | 0.93 | GAA (0.46) | GAAL3MBTL1CA1CA2CA12 | |
| SCHEMBL28412243 | 0.91 | TDP1 (0.46) | GAACA1CA2CA12CA9 | |
| SCHEMBL7713828 | 0.91 | TDP1 (0.46) | GAACA1CA2CA12CA9 | |
| SCHEMBL16295389 | 0.91 | TDP1 (0.46) | GAACA1CA2CA12CA9 | |
| SCHEMBL9765342 | 0.87 | GAA (0.52) | GAACA1CA2CA12CA9 | |
| SCHEMBL15201198 | 0.87 | GAA (0.52) | GAACA1CA2CA12CA9 | |
| SCHEMBL110028 | 0.84 | — | — | |
| SCHEMBL9489754 | 0.84 | L3MBTL1 (0.53) | L3MBTL1CA1CA2CA12CA9 | |
| SCHEMBL2746552 | 0.82 | PTGS1 (0.42) | GAAL3MBTL1CA1CA2CA12 | |
| SCHEMBL31264254 | 0.81 | GAA (0.45) | GAACA2CA9TGFBR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103123672-A | Target gene Rv0233 screened by antituberculous inhibitor and application | UNIV HUAZHONG AGRICULTURAL | 2013-05-29 | — | — | CN | claimed |
| CN-117619285-A | Preparation method of thermochromic microcapsule and thermochromic ink | 福建泰新泉科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-111349233-B | Biodegradable alternating aliphatic polyester amide and preparation method thereof | 东华大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-111349233-A | Biodegradable alternating aliphatic polyester amide and preparation method thereof | 东华大学 | 2020-06-30 | — | — | CN | disclosed |
| EP-3008517-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2016-04-20 | — | — | EP | disclosed |
| EP-3008518-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics NV (BE) | 2016-04-20 | — | — | EP | disclosed |
| WO-2015086659-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR AND MONOMER | AGFA GRAPHICS NV (BE) | 2015-06-18 | — | — | WO | disclosed |
| WO-2014198820-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014198823-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2014-12-18 | — | — | WO | disclosed |
| EP-1889845-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SmithKline Beecham P.L.C. (GB) | 2008-02-20 | — | — | EP | disclosed |
| US-7160907-B2 | Pleuromutilin derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-01-09 | — | — | US | disclosed |
| EP-1538150-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2005-06-08 | — | — | EP | disclosed |
| EP-1351959-B1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | disclosed |
| US-6900345-B2 | Pleuromutilin derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-05-31 | — | — | US | disclosed |
| US-20050096357-A1 | Novel pleuromutilin derivatives | SMITHKLINE BEECHAM P.L.C. | 2005-05-05 | — | — | US | disclosed |
| US-20040024059-A1 | Novel pleuromutilin derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-02-05 | — | — | US | disclosed |
| EP-1351959-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002030929-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |
| EP-0009866-B1 | PHENOLIC ESTERAMIDE ANTIOXIDANTS AND THEIR USE | UNIROYAL, INC. (US) | 1982-08-04 | — | — | EP | disclosed |
| EP-0009866-A1 | Phenolic esteramide antioxidants and their use | UNIROYAL, INC. (US) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024059-A1 | Novel pleuromutilin derivatives | PLEC, MLNR, FABP2 | GAA 1204/4885L3MBTL1 3568/4885CA1 4247/4885 |
| US-20050096357-A1 | Novel pleuromutilin derivatives | FABP2, PLEC, MLNR | GAA 1541/4885L3MBTL1 3624/4885CA1 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.