SCHEMBL9489754

SCHEMBL9489754

O=C(NCCCO)C(=O)NCCCO

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
PTGS1 P23219 1/20 0.43
KCNH2 Q12809 1/20 0.43
POLB P06746 1/20 0.41
HTT P42858 2/20 0.41
EPHX2 P34913 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
NAAA Q02083 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10774227 0.88 TDP1 (0.52) L3MBTL1CA1CA2CA12CA9
SCHEMBL18884998 0.87 L3MBTL1 (0.46) L3MBTL1CA1CA2CA12CA9
SCHEMBL18808374 0.87 EPHX1 (0.50) L3MBTL1PTGS1KCNH2NAAA
SCHEMBL18885000 0.87 ACHE (0.53) L3MBTL1EPHX2NAAA
SCHEMBL583703 0.86 L3MBTL1 (0.44) L3MBTL1CA1CA2CA12CA9
SCHEMBL4697573 0.84 GAA (0.47) L3MBTL1CA1CA2CA12CA9
SCHEMBL13589542 0.84 KDM4E (0.44) L3MBTL1CA1CA2CA12CA9
SCHEMBL16805870 0.83 L3MBTL1 (0.43) L3MBTL1CA1CA2CA12CA9
SCHEMBL692078 0.81 EPHX1 (0.52) CA1CA2CA12CA9PTGS1
SCHEMBL76690 0.80 ALDH1A1 (0.52) L3MBTL1POLBHTTEPHX2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5229445-A Stabilized against thermal degradation by inclusion of sterically hindered symmetrical diesters of phenolic alkanoic acids and N,N*-di/hydroxyalkyl/oxalamide SHELL OIL COMPANY (US) 1993-07-20 US claimed
US-4645853-A Hindered phenolic oxamide compounds and stabilized compositions ICI AMERICAS INC. (US) 1987-02-24 US claimed
CN-112912798-B Lithographic printing plate precursor 易客发有限公司 2024-03-29 CN disclosed
CN-117619285-A Preparation method of thermochromic microcapsule and thermochromic ink 福建泰新泉科技有限公司 2024-03-01 CN disclosed
US-20230211599-A1 Lithographic Photopolymer Printing Plate Precursor with Improved Daylight Stability AGFA OFFSET BV (BE) 2023-07-06 US disclosed
US-20230211599-A1 Lithographic Photopolymer Printing Plate Precursor with Improved Daylight Stability AGFA OFFSET BV (BE) 2023-07-06 US disclosed
US-11584118-B2 Lithographic printing plate precursor AGFA OFFSET BV (BE) 2023-02-21 US disclosed
US-11584118-B2 Lithographic printing plate precursor AGFA OFFSET BV (BE) 2023-02-21 US disclosed
US-20220009219-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR ECO3 BV (BE) 2022-01-13 US disclosed
WO-2021249754-A1 LITHOGRAPHIC PHOTOPOLYMER PRINTING PLATE PRECURSOR WITH IMPROVED DAYLIGHT STABILITY AGFA OFFSET BV (BE) 2021-12-16 WO disclosed
EP-3922462-A1 LITHOGRAPHIC PHOTOPOLYMER PRINTING PLATE PRECURSOR WITH IMPROVED DAYLIGHT STABILITY AGFA OFFSET BV (BE) 2021-12-15 EP disclosed
EP-0245631-B1 CHEMICAL PROCESS FOR THE PREPARATION OF OXAMIDE DERIVATIVES. ENICHEM ANIC S.p.A. (IT) 1990-08-01 EP disclosed
EP-0245631-A2 Chemical process for the preparation of oxamide derivatives. ENICHEM ANIC S.p.A. (IT) 1987-11-19 EP disclosed
US-4645853-A Hindered phenolic oxamide compounds and stabilized compositions ICI AMERICAS INC. (US) 1987-02-24 US disclosed
EP-0002616-B1 OXAMIDE DERIVATIVES, THEIR USE IN STABILIZING ORGANIC MATERIALS AND STABILIZED ORGANIC MATERIALS CONTAINING THE SAID OXAMIDE DERIVATIVES UNIROYAL, INC. (US) 1983-03-30 EP disclosed
EP-0002616-A1 Oxamide derivatives, their use in stabilizing organic materials and stabilized organic materials containing the said oxamide derivatives UNIROYAL, INC. (US) 1979-06-27 EP disclosed
US-4154723-A N,N*-BIS/ALKYLHYDROXYPHENYL/ALKANOYLOXYHYDROCARBYL/OXAMIDE, ANTIOXIDANT, POLYMERS MONSANTO COMPANY (US) 1979-05-15 US disclosed
US-4145556-A N,N*-BIS(ALKYLHYDROXYPHENYL)ALKANOYLOXY-HYDROCARBYL)OXAMIDES MONSANTO COMPANY (US) 1979-03-20 US disclosed
US-4101473-A Solid particle-form polymerizable polymeric material and compositions, structures and methods of employing and producing the same STORY CHEMICAL CORPORATION (US) 1978-07-18 US disclosed
US-3947426-A Solid particle-form polymerizable polymeric material and compositions, structures and methods of employing and producing the same STORY CHEMICAL CORPORATION (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009219-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR LCP1, COLGALT1, LAS1L L3MBTL1 34/4885CA1 3598/4885CA2 4015/4885
US-11584118-B2 Lithographic printing plate precursor LCP1, LAS1L, ILK L3MBTL1 36/4885CA1 3536/4885CA2 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.