SCHEMBL4698

SCHEMBL4698

Ic1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.67
TSHR P16473 1/20 0.67
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MAOA P21397 1/20 0.56
APP P05067 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
GSTP1 P09211 1/20 0.46
SOS1 Q07889 1/20 0.46
CA9 Q16790 1/20 0.46
PARP10 Q53GL7 1/20 0.46
PLA2G2A P14555 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
NLRP3 Q96P20 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27597197 0.91 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28092325 0.89 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3841043 0.88 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3845620 0.88 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL2883028 0.88 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL20879853 0.87 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL122719 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL22129853 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3893562 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL435149 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085300-B Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2023-09-15 CN claimed
CN-114085300-A Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2022-02-25 CN claimed
WO-1994005618-A1 PROCESS FOR THE PRODUCTION OF DIIODOKETONES EASTMAN KODAK COMPANY (US) 1994-03-17 WO claimed
US-4922010-A Processes for preparing 2-substituted propionic acid and derivatives thereof UBE INDUSTRIES, LTD. (JP) 1990-05-01 US claimed
JP-62185047-A None JP disclosed
JP-62161745-A None JP disclosed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 WO disclosed
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) 2024-12-26 US disclosed
EP-3808747-B1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL (JP) 2024-12-18 EP disclosed
CN-118946340-A Curable composition for dentistry having excellent color tone adaptability 可乐丽则武齿科株式会社 2024-11-12 CN disclosed
EP-0488602-A1 Aryl derivatives ZENECA LIMITED (GB) 1992-06-03 EP disclosed
EP-0415982-A1 METHOD OF PREPARING AROMATIC ETHERS FROM IODOAROMATIC COMPOUNDS. EASTMAN KODAK CO (US) 1991-03-13 EP disclosed
US-4922010-A Processes for preparing 2-substituted propionic acid and derivatives thereof UBE INDUSTRIES, LTD. (JP) 1990-05-01 US disclosed
WO-1989010912-A1 METHOD OF PREPARING AROMATIC ETHERS FROM IODOAROMATIC COMPOUNDS EASTMAN KODAK COMPANY (US) 1989-11-16 WO disclosed
WO-1989008630-A1 METHOD FOR THE HALOGENATION OF AROMATIC COMPOUNDS ZENOVA AB (SE) 1989-09-21 WO disclosed
JP-S62185047-A PRODUCTION OF DIPHENYL ETHER CARBOXYLIC ACID ASAHI CHEM IND CO LTD 1987-08-13 JP disclosed
JP-S62161745-A PRODUCTION OF DIPHENYL ETHER CARBOXYLIC ACID ESTER ASAHI CHEM IND CO LTD 1987-07-17 JP disclosed
US-4567280-A NITROGEN DIOXIDE; BY-PRODUCT INHIBITION UBE INDUSTRIES, LTD. (JP) 1986-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND EGLN3, DHPS, EGLN2 LTA4H 323/4885TSHR 4705/4885NR1H2 943/4885
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT LTA4H 669/4885TSHR 4739/4885NR1H2 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.