Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702445 | 0.97 | TDP1 (0.57) | TDP1LMNASMN1; SMN2ALOX12BCHE | |
| SCHEMBL3106205 | 0.94 | TDP1 (0.51) | TDP1LMNASMN1; SMN2ALOX12KMT2A | |
| SCHEMBL20990655 | 0.88 | TDP1 (0.45) | TDP1LMNASMN1; SMN2SCN1ASCN2A | |
| SCHEMBL915835 | 0.86 | TDP1 (0.44) | TDP1LMNASMN1; SMN2KMT2AMGLL | |
| SCHEMBL1949595 | 0.82 | ALOX12 (0.38) | SMN1; SMN2ALOX12MGLL | |
| SCHEMBL13748507 | 0.82 | ALOX12 (0.38) | SMN1; SMN2ALOX12MGLL | |
| SCHEMBL1280224 | 0.80 | ALOX12 (0.37) | SMN1; SMN2ALOX12MGLL | |
| SCHEMBL4699911 | 0.80 | ALDH1A1 (0.47) | TDP1LMNASMN1; SMN2KMT2AMGLL | |
| SCHEMBL4066802 | 0.79 | KMT2A (0.48) | TDP1LMNASMN1; SMN2ALOX12KMT2A | |
| SCHEMBL19309377 | 0.78 | KMT2A (0.53) | TDP1LMNASMN1; SMN2ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |