Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109277 | 0.94 | GLA (0.33) | GLAMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL917156 | 0.87 | GLA (0.34) | MAPTGLAMEN1LMNACYP3A4 | |
| SCHEMBL4821013 | 0.84 | ALOX12 (0.33) | ALOX12MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4702471 | 0.84 | NAAA (0.47) | MAPTMAPK1NPSR1L3MBTL1ALOX12 | |
| SCHEMBL1949595 | 0.83 | ALOX12 (0.38) | ALOX12CYP3A4PRKCAMGLLNAAA | |
| SCHEMBL13748507 | 0.83 | ALOX12 (0.38) | ALOX12CYP3A4PRKCAMGLLNAAA | |
| SCHEMBL917125 | 0.83 | MEN1 (0.36) | GLAMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL1280224 | 0.81 | ALOX12 (0.37) | ALOX12CYP3A4MGLL | |
| SCHEMBL4698358 | 0.81 | PRKCA (0.39) | MAPTMAPK1L3MBTL1ALOX12LMNA | |
| SCHEMBL4698375 | 0.81 | NAAA (0.43) | MAPK1ALOX12MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |