Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701139 | 0.93 | LMNA (0.36) | LMNA | |
| SCHEMBL4700325 | 0.88 | PPARA (0.30) | — | |
| SCHEMBL4696405 | 0.86 | MMP1 (0.39) | — | |
| SCHEMBL4696952 | 0.85 | — | — | |
| SCHEMBL4696638 | 0.84 | — | — | |
| SCHEMBL926345 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL5148275 | 0.82 | CYP1A2 (0.31) | LMNA | |
| SCHEMBL4700764 | 0.81 | LMNA (0.37) | LMNA | |
| SCHEMBL4700775 | 0.81 | — | — | |
| SCHEMBL8222845 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | claimed |