Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698747 | 1.00 | F2 (0.45) | F2PRSS1NAMPTHDAC1CASP3 | |
| SCHEMBL3335569 | 0.83 | MASP2 (0.37) | NAMPTCASP3CPB1MASP2 | |
| SCHEMBL3340333 | 0.83 | MASP2 (0.37) | NAMPTCASP3CPB1MASP2 | |
| SCHEMBL4694722 | 0.67 | TAAR1 (0.36) | EPHX1ELANENPC1RAB9AGAA | |
| SCHEMBL4696954 | 0.66 | F11 (0.41) | ELANESMN1; SMN2 | |
| SCHEMBL18291413 | 0.65 | KDM4E (0.56) | MAPTSMN1; SMN2HIF1A | |
| SCHEMBL3936679 | 0.62 | MAOB (0.56) | SMN1; SMN2 | |
| SCHEMBL16609238 | 0.62 | EPHX2 (0.49) | F2PRSS1NAMPTCPB1MASP2 | |
| SCHEMBL23793677 | 0.62 | MASP2 (0.57) | F2MASP2 | |
| Hydrochloric Acid SCHEMBL28571397 | 0.61 | MASP2 (0.56) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |