Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3330879 | 0.81 | CASP3 (0.34) | GAAALDH1A1 | |
| SCHEMBL4696831 | 0.77 | TPSAB1 (0.39) | TAAR1NPC1RAB9AGAAELANE | |
| SCHEMBL4697607 | 0.70 | TPSAB1 (0.48) | RAB9AALDH1A1TPSAB1P2RX4 | |
| SCHEMBL4698784 | 0.67 | TPSAB1 (0.44) | TAAR1NPC1RAB9AEPHX1ALDH1A1 | |
| SCHEMBL4698740 | 0.67 | F2 (0.45) | NPC1RAB9AGAAELANEEPHX1 | |
| SCHEMBL4698747 | 0.67 | F2 (0.45) | NPC1RAB9AGAAELANEEPHX1 | |
| Phenformin SCHEMBL8424 | 0.62 | NPC1 (0.52) | TAAR1NPC1RAB9AGAAL3MBTL1 | |
| Phenformin SCHEMBL12487086 | 0.62 | NPC1 (0.52) | TAAR1NPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL4697341 | 0.62 | TPSAB1 (0.58) | TPSAB1P2RX4 | |
| SCHEMBL4697345 | 0.62 | TPSAB1 (0.58) | TPSAB1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |