Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 5/20 | 0.31 |
| ▸ | PER2 | O15055 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411138 | 0.82 | GRIN2D (0.38) | ROCK2TDO2KDM4E | |
| SCHEMBL469807 | 0.70 | CNR2 (0.52) | CNR2 | |
| SCHEMBL10068626 | 0.69 | GRM5 (0.41) | GRM5 | |
| SCHEMBL13424162 | 0.69 | IDH1 (0.38) | GRM5 | |
| SCHEMBL19864946 | 0.68 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL46307 | 0.65 | GPR119 (0.41) | GRM5 | |
| SCHEMBL19341535 | 0.64 | MAPT (0.51) | LMNACNR2 | |
| SCHEMBL10281036 | 0.64 | MAPT (0.47) | KDM4ELMNACNR2 | |
| SCHEMBL16498267 | 0.64 | GRIN2D (0.38) | KDM4ELMNA | |
| SCHEMBL1557357 | 0.64 | AKR1C3 (0.41) | KDM4EGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |