Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.37 |
| ▸ | CTSS | P25774 | 10/20 | 0.37 |
| ▸ | CTSB | P07858 | 9/20 | 0.37 |
| ▸ | CTSK | P43235 | 8/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704327 | 0.87 | CTSL (0.51) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4701851 | 0.85 | CTSL (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4698882 | 0.79 | CTSL (0.42) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4703890 | 0.77 | CTSS (0.40) | CTSLCTSSCTSBCTSKALDH1A1 | |
| SCHEMBL4705295 | 0.76 | CTSL (0.45) | CTSLCTSSCTSBCTSKRET | |
| SCHEMBL4704891 | 0.75 | CTSL (0.37) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4698649 | 0.74 | CTSL (0.48) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4703666 | 0.73 | CTSL (0.47) | CTSLCTSSCTSBCTSKRET | |
| SCHEMBL5872529 | 0.73 | CTSL (0.47) | CTSLCTSSCTSBCTSKRET | |
| SCHEMBL4698985 | 0.73 | CTSL (0.57) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-10-01 | — | — | EP | disclosed |