SCHEMBL4699243

SCHEMBL4699243

CCNc1ccc(-c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.64
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
ADRA2A P08913 2/20 0.46
FFAR1 O14842 3/20 0.46
MAPT P10636 3/20 0.45
RAD51 Q06609 1/20 0.45
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MITF O75030 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN11 Q06124 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22156281 1.00 LMNA (0.64) LMNAMEN1KMT2AFNTAFNTB
Hydrochloric Acid SCHEMBL27595921 0.98 LMNA (0.62) LMNAMEN1KMT2AFNTAFNTB
Biphenyl SCHEMBL8912883 0.93 LMNA (0.61) LMNAMEN1KMT2AFNTAFNTB
SCHEMBL7038850 0.93 LMNA (0.61) LMNAMEN1KMT2AFNTAFNTB
SCHEMBL7012895 0.90 LMNA (0.56) LMNAMEN1KMT2AFNTAFNTB
SCHEMBL11544937 0.90 LMNA (0.56) LMNAMEN1KMT2AFNTAFNTB
SCHEMBL24303801 0.86 LMNA (0.50) LMNAMEN1KMT2AMAPTRAD51
SCHEMBL28323614 0.86 MMP3 (0.58) LMNAMEN1KMT2AADRA2AMAPT
SCHEMBL13586888 0.86 LMNA (0.55) LMNAMEN1KMT2AFNTAFNTB
SCHEMBL30873945 0.85 NR3C2 (0.51) LMNAMEN1KMT2AFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986996-A2 A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST Abiogen Pharma S.p.A. (IT) 2008-11-05 EP claimed
WO-2007088571-A2 A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST ABIOGEN PHARMA S.P.A. (IT) 2007-08-09 WO claimed
CN-117327045-A DASA compound, preparation method thereof and application thereof in photochromic dye 中山大学 2024-01-02 CN disclosed
WO-2021135182-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
US-20200231580-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME DOOSAN CORPORATION (KR) 2020-07-23 US disclosed
WO-2020062375-A1 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF 武汉尚赛光电科技有限公司 2020-04-02 WO disclosed
EP-2418536-B1 LIQUID CRYSTAL DISPLAY DEVICE and COMPOSITION FOR FORMING a POLYMER LAYER SHARP KK (JP) 2014-09-17 EP disclosed
CN-102149450-A Water purification membranes with improved fouling resistance UNIV TEXAS 2011-08-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231580-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME SLCO4C1, SLCO2A1, POU2F1 LMNA 3169/4885MEN1 2343/4885KMT2A 2200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.