Biphenyl

Biphenyl

SCHEMBL8912883

CCNc1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
ADRA2A P08913 2/20 0.47
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TSHR P16473 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038850 0.95 LMNA (0.61) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL22156281 0.93 LMNA (0.64) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL4699243 0.93 LMNA (0.64) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL20852333 0.92 LMNA (0.61) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL4916223 0.92 LMNA (0.61) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL7709 0.92
Hydrochloric Acid SCHEMBL27595921 0.91 LMNA (0.62) LMNAALDH1A1MAPTADRA2AMEN1
SCHEMBL7707049 0.90 LMNA (0.59) LMNAALDH1A1MAPTADRA2AMEN1
Iodide SCHEMBL17710408 0.90 LMNA (0.59) LMNAALDH1A1MAPTADRA2AMEN1
Ammonia Solution, Strong SCHEMBL8429752 0.90 LMNA (0.59) LMNAALDH1A1MAPTADRA2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5609970-A GENERATING ELECTROMAGNETIC RADIATION POLAROID CORPORATION (US) 1997-03-11 US claimed
WO-2019170163-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS 东莞市均成高新材料有限公司 2019-09-12 WO disclosed