Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | CALML3 | P27482 | 7/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SDHA | P31040 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412126 | 0.84 | MAOA (0.46) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL13942149 | 0.84 | MAOA (0.46) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL13942140 | 0.77 | CYP2E1 (0.52) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL5945278 | 0.77 | CYP2E1 (0.52) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL4578360 | 0.76 | GRM2 (0.64) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL4901632 | 0.75 | MAOB (0.61) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL2897920 | 0.75 | CALML3 (0.50) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL16685649 | 0.75 | CALML3 (0.50) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL5945387 | 0.73 | CALML3 (0.39) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL7297166 | 0.73 | GRM2 (0.63) | MAOAMAOBCALML3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |