Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | CALML3 | P27482 | 7/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SDHA | P31040 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942149 | 0.84 | MAOA (0.46) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL469925 | 0.84 | MAOA (0.46) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL28380585 | 0.82 | MAOA (0.57) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL16685649 | 0.80 | CALML3 (0.50) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL2897920 | 0.80 | CALML3 (0.50) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL16686193 | 0.78 | MAOB (0.36) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL16686195 | 0.78 | MAOB (0.36) | MAOAMAOBCALML3GRM2LMNA | |
| SCHEMBL30768255 | 0.77 | CALML3 (0.65) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL30468631 | 0.77 | CALML3 (0.65) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL29021122 | 0.77 | CALML3 (0.65) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120190713-A1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190713-A1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH (US) | 2012-07-26 | — | — | US | disclosed |
| US-8178683-B2 | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-05-15 | — | — | US | disclosed |
| US-8178683-B2 | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-05-15 | — | — | US | disclosed |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
| US-20100204477-A1 | Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones | MICURX PHARMACEUTICALS, INC. (KY) | 2010-08-12 | — | — | US | disclosed |
| US-20100204477-A1 | Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones | MICURX PHARMACEUTICALS, INC. (KY) | 2010-08-12 | — | — | US | disclosed |
| US-20090048305-A1 | Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections | SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) | 2009-02-19 | — | — | US | disclosed |
| US-20090048305-A1 | Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections | SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190713-A1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | OXA1L, OGFOD1, OLA1 | MAOA 1026/4885MAOB 765/4885CALML3 4723/4885 |
| US-20100204477-A1 | Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones | DHPS, FDPS, CYP2F1 | MAOA 1004/4885MAOB 772/4885CALML3 4182/4885 |
| US-20090048305-A1 | Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections | OXA1L, OGFOD1, OLA1 | MAOA 1026/4885MAOB 765/4885CALML3 4723/4885 |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | NISCH, SI, VIP | MAOA 853/4885MAOB 427/4885CALML3 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.