Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699811 | 1.00 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4700187 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4700007 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19449716 | 0.81 | CTDSP1 (0.71) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL17560817 | 0.79 | CTDSP1 (0.69) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4701009 | 0.79 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4701004 | 0.79 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4698438 | 0.77 | LMNA (0.51) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4699521 | 0.77 | MAPT (0.61) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4700011 | 0.74 | MAPT (0.59) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |