Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701009 | 1.00 | KMT2A (0.74) | KMT2AMEN1TRPM5LMNAALOX12 | |
| SCHEMBL4698438 | 0.81 | LMNA (0.51) | KMT2AMEN1TRPM5LMNAALOX12 | |
| SCHEMBL18251625 | 0.80 | CYP1A2 (0.68) | KMT2AMEN1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL4699811 | 0.79 | MAPT (0.74) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL4699516 | 0.79 | MAPT (0.74) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL18245478 | 0.78 | CYP1A2 (0.66) | KMT2AMEN1LMNASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL18245477 | 0.78 | CYP1A2 (0.66) | KMT2AMEN1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL4701015 | 0.76 | KMT2A (0.61) | KMT2AMEN1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL13563559 | 0.74 | MEN1 (0.58) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL18251633 | 0.74 | CYP1A2 (0.67) | KMT2AMEN1LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016198472-A1 | TOPICAL DELIVERY SYSTEM | HPF IP HOLDING S.A. (LU) | 2016-12-15 | — | — | WO | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| WO-2016198472-A1 | TOPICAL DELIVERY SYSTEM | HPF IP HOLDING S.A. (LU) | 2016-12-15 | — | — | WO | disclosed |
| WO-2015097513-A1 | TOPICAL PRODUCTS FOR AMINOGUANIDINES | ANAMAR DERMA AB (SE) | 2015-07-02 | — | — | WO | disclosed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |