SCHEMBL4700042

SCHEMBL4700042

NS(=O)(=O)c1cccc(-n2[nH]c(C(=O)O)cc2=O)c1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALKBH5 Q6P6C2 17/20 0.63
▸ CA1 P00915 3/20 0.44
▸ CA2 P00918 3/20 0.44
▸ CA7 P43166 2/20 0.44
▸ CA12 O43570 2/20 0.43
▸ CA9 Q16790 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL693103 0.88 ALKBH5 (0.64) ALKBH5
SCHEMBL10393940 0.82 ALKBH5 (0.57) ALKBH5
SCHEMBL6807273 0.80 ALKBH5 (0.69) ALKBH5
SCHEMBL951472 0.79 ALKBH5 (0.73) ALKBH5
SCHEMBL9789614 0.79 CA1 (0.49) ALKBH5CA1CA2CA7CA12
SCHEMBL11300860 0.79 ALKBH5 (0.72) ALKBH5
SCHEMBL10952541 0.77 ALKBH5 (1.00) ALKBH5
SCHEMBL1265785 0.76 ALKBH5 (0.55) ALKBH5
SCHEMBL67421 0.74 ALKBH5 (0.66) ALKBH5
SCHEMBL8990127 0.74 ALKBH5 (0.54) ALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000123-B1 USE OF REACTIVE DYES FOR DYEING HAIR BASF SE (DE) 2008-09-10 — — EP disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 — — US disclosed
EP-0929610-B1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-08-28 — — EP disclosed
EP-1027387-B1 DOUBLE REACTIVE DYES DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-02-06 — — EP disclosed
EP-1086180-A1 TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 2001-03-28 — — EP disclosed
US-6197941-B1 TRIAZINE, METALLIZED, AZO, ANTHRAQUINONE, FORMAZAN, PHTHALOCYANINE, AND DIOXAZINE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 — — US disclosed
US-6159250-A Doubled reactive dyes BASF AKTIENGESELLSCHAFT (DE) 2000-12-12 — — US disclosed
EP-0733680-B1 Reactive dyes with a benzo-anellated heterocycle as reactive group BASF AG (DE) 2000-01-05 — — EP disclosed
WO-1999064520-A1 TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-12-16 — — WO disclosed
US-5929217-A FOR DYEING OR PRINTING SUBSTRATES HAVING HYDROXYL GROUPS OR NITROGEN ATOMS BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 — — US disclosed
EP-0374911-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 — — EP disclosed
EP-0361440-A1 Water soluble fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-04 — — EP disclosed
EP-0354409-A1 Fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-14 — — EP disclosed
EP-0352682-A2 Twice reactive dyes and benzyl compounds as their intermediary products BASF Aktiengesellschaft (DE) 1990-01-31 — — EP disclosed
US-4873320-A COLORFASTNESS; FOR COTTON AND CELLULOSE FIBER MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-10 — — US disclosed
EP-0212264-B1 COLOURED WATER SOLUBLE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-31 — — EP disclosed
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 — — US disclosed
EP-0212264-A1 Coloured water soluble compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 — — EP disclosed
EP-0119441-B1 REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS BASF Aktiengesellschaft (DE) 1987-02-25 — — EP disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 — — EP disclosed
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